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Antigenic Specificity | RAGE |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Rabbit IgG polyclonal antibody for Advanced glycosylation end product-specific receptor(AGER) detection. Tested with WB, IHC-P, IHC-F in Human, Mouse, Rat. Background: The receptor for advanced glycation end products(RAGE) is a multi-ligand member of the immunoglobulin superfamily of cell surface molecules. It interacts with distinct molecules implicated in homeostasis, development and inflammation, and certain diseases such as diabetes and Alzheimer's disease. RAGE is also a central cell surface receptor for amphoterin and EN-RAGE. RAGE is associated with sustained NF-kappaB activation in the diabetic microenvironment and has a central role in sensory neuronal dysfunction. Moreover, RAGE propagates cellular dysfunction in seve |
Immunogen | Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human RAGE (174-192aa KEQTRRHPETGLFTLQSEL), different from the related mouse and rat sequences by two amino acids. |
Other Names | [Advanced glycosylation end product-specific receptor; advanced glycosylation end product-specific receptor; Advanced glycosylation end product-specific receptor; AGER; MGC2235; MGC22357; RAGE_HUMAN; Receptor for advanced glycation endproducts; Receptor for advanced glycosylation end products], [AGER; AGER; RAGE; RAGE] |
Gene, Accession # | [AGER], Gene ID: 177, NCBI: Q15109.1, UniProt: Q15109 |
Catalog # | MBS175241 |
Price | $315 |
Order / More Info | RAGE Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |