MMP-9 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMMP-9
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA), Immunohistochemistry (IHC) Paraffin
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DescriptionSpecificity: MMP-9 antibody detects endogenous levels of total MMP-9. Function: May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.Subunit Structure: Exists as monomer or homodimer; disulfide-linked. Exists also as heterodimer with a 25 kDa protein. Macrophages and transformed cell lines produce only the monomeric form. Interacts with ECM1.Post-translational Modifications: Processing of the precursor yields different act
ImmunogenImmunogen: A synthesized peptide derived from human MMP-9 Subcellular Location: Secreted, Extracellular Space, Extracellular Matrix. Tissue Specificity: Produced by normal alveolar macrophages and granulocytes. Predicted Cross Reactivity: Pig, Horse Similarity: Pig (82%), Horse (82%)
Other Names[82 kDa matrix metalloproteinase-9; 92 kDa gelatinase; 92 kDa type IV collagenase; CLG 4B; CLG4B; Collagenase Type 4 beta; Collagenase type IV 92 KD; EC 3.4.24.35; Gelatinase 92 KD; Gelatinase B; Gelatinase beta; GelatinaseB; GELB; Macrophage gelatinase; MANDP2; Matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase); Matrix Metalloproteinase 9; MMP 9; MMP-9; MMP9; MMP9_HUMAN; Type V collagenase]
Gene, Accession #[MMP-9], Gene ID: 4318, NCBI: NP_004985.2, UniProt: P14780
Catalog #MBS9601401
Price$240, $280
Order / More InfoMMP-9 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesBai Y, Wang J, Han J, Xie XL, Ji CG, Yin J, Chen L, Wang CK, Jiang XY, Qi W, Jiang HQ; Journal: Mol Carcinog. BCL2L10 inhibits growth and metastasis of hepatocellular carcinoma both in vitro and in vivo. Liu Y, Zheng J, Zhang Y, Wang Z, Yang Y, Bai M, Dai Y; Journal: Neurochem Res. Fucoxanthin Activates Apoptosis via Inhibition of PI3K/Akt/mTOR Pathway and Suppresses Invasion and Migration by Restriction of p38-MMP-2/9 Pathway in Human Glioblastoma Cells. Wu Z, Wang T, Fang M, Huang W, Sun Z, Xiao J, Yan W; Journal: Biochem Biophys Res Commun. MFAP5 promotes tumor progression and bone metastasis by regulating ERK/MMP signaling pathways in breast cancer. Jie L, Pengcheng Q, Qiaoyan H, Linlin B, Meng Z, Fang W, Min J, Li Y, Ya Z, Qian Y, Siwang W; Journal: Eur J Pharmacol. Dencichine ameliorates kidney injury in induced type II diabetic nephropathy via the TGF-beta/Smad signalling pathway. Shao Q, Zhang P, Ma Y, Lu Z, Meng J, Li H, Wang X, Chen D, Zhang M, Han Y, Liu H, Ma S; Journal: Gene. MicroRNA-139-5p affects cisplatin sensitivity in human nasopharyngeal carcinoma cells by regulating the epithelial-to-mesenchymal transition.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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