TTK (N-term), 6-35 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TTK (N-term), 6-35 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: monkey) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This TTK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-35 amino acids from the N-terminal region of human TTK. This gene encodes a dual specificity protein kinase withthe ability to phosphorylate tyrosine, serine and threonine.Associated with cell proliferation, this protein is essential forchromosome alignment at the centromere during mitosis and isrequired for centrosome duplication. It has been found to be acritical mitotic checkpoint protein for accurate segregation ofchromosomes during mitosis. Tumorigenesis may occur when thisprotein fails to degrade and produces excess centrosomes resultingin aberrant mitotic spindles. Alternative splicing results in |
| Immunogen | n/a |
| Other Names | [Dual specificity protein kinase TTK; Phosphotyrosine picked threonine-protein kinase; PYT; TTK; MPS1; MPS1L1] |
| Gene, Accession # | [TTK], Gene ID: 7272, NCBI: NP_001160163.1, UniProt: P33981 |
| Catalog # | MBS9208171 |
| Price | $165, $370 |
| Order / More Info | TTK (N-term), 6-35 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Cui, Y., et al. J. Biol. Chem. 285(43):32988-32998(2010) Maciejowski, J., et al. J. Cell Biol. 190(1):89-100(2010) Santaguida, S., et al. J. Cell Biol. 190(1):73-87(2010) Hewitt, L., et al. J. Cell Biol. 190(1):25-34(2010) Lan, W., et al. J. Cell Biol. 190(1):21-24(2010) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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