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Antigenic Specificity | PPP2R2A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total PPP2R2A protein. Protein phosphatase 2A subunit B isoform R2-a (PPP2R2A) is the component of regulatory subunit B of serine/threonine protein phosphatase 2A (PP2A). PPP2R2A belongs to the R2/B55/PR55 family of regulatory subunit B (1). Evidence suggests that subunit PPP2R2A enhances TGF-b, Activin, and Nodal signaling pathways (7) and may play an important role in cell cycle regulation (2-4). PPP2R2A/PP2A, B55-a/PR55-a isoform interacts with the type I TGF-b receptors via unique WD-40 repeats (5) that contribute to the anti-proliferative function of TGF-b receptors (6). |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant protein of human PPP2R2A. |
Other Names | [B55-ALPHA; B55A; FLJ26613; MGC52248; PR52A] |
Gene, Accession # | [PPP2R2A], Gene ID: 5520, NCBI: NP_001171062.1, UniProt: P63151 |
Catalog # | MBS9403018 |
Price | $255 |
Order / More Info | PPP2R2A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |