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Antigenic Specificity | Phospho-Mouse CASP3 (S26) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Dot Blot (DB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This mouse CASP3 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S26 of mouse CASP3. This gene encodes a protein which is a member of thecysteine-aspartic acid protease (caspase) family. Sequentialactivation of caspases plays a central role in the execution-phaseof cell apoptosis. Caspases exist as inactive proenzymes whichundergo proteolytic processing at conserved aspartic residues toproduce two subunits, large and small, that dimerize to form theactive enzyme. This protein cleaves and activates caspases 6, 7 and9, and the protein itself is processed by caspases 8, 9 and 10. Itis the predominant caspase involved in |
Immunogen | n/a |
Other Names | [Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; LICE; Protein Yama; SREBP cleavage activity 1; SCA-1; Caspase-3 subunit p17; Caspase-3 subunit p12; Casp3; Cpp32] |
Gene, Accession # | [Casp3], Gene ID: 12367, NCBI: NP_033940.1, UniProt: P70677 |
Catalog # | MBS9210225 |
Price | $165, $370 |
Order / More Info | Phospho-Mouse CASP3 (S26) Antibody from MYBIOSOURCE INC. |
Product Specific References | Srikanth, C.V., et al. Science 330(6002):390-393(2010) Li, F., et al. Cell Stem Cell 7(4):508-520(2010) Wang, L., et al. J. Neurosci. 30(39):13201-13210(2010) Gascon, E., et al. J. Neurosci. 30(37):12414-12423(2010) Bohsali, A., et al. BMC Microbiol. 10, 237 (2010) : |