Edit |   |
Antigenic Specificity | CD18 |
Clone | [1A3/2A10] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Frozen/Paraffin, Immunocytochemistry (ICC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Description: Mouse IgG monoclonal antibody for CD18 detection. Tested with WB, IHC-P, IHC-F, ICC, FCM in Human.Background: ITGB2 (INTEGRIN, BETA-2), also known as CD18, is a protein that in humans is encoded by the ITGB2 gene. ITGB2 is an integrin protein that belongs to the class of cell membrane glycoproteins. The beta-2 integrin chain gene is designated ITGB2 and the leukocyte antigen has been designated CD18. The ITGB2 gene is mapped to 21q22.3. The expression of CD18 is increased in lymphoblastoid cells from persons with Down syndrome, consistent with the location of the gene on chromosome 21. In humans lack of ITGB2 causes Leukocyte Adhesion Deficiency, a disease defined by a l |
Immunogen | Immunogen: E Coli-derived human CD18 recombinant protein (Position: Q404-S769). Human CD18 shares 76% amino acid (aa) sequence identity with mouse CD18. |
Other Names | [Integrin beta-2; Cell surface adhesion glycoproteins LFA-1/CR3/p150, 95 subunit beta; Complement receptor C3 subunit beta; CD18; ITGB2; CD18; MFI7; Integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)] |
Gene, Accession # | [CD18], Gene ID: 3689, NCBI: NP_000202.3, UniProt: P05107 |
Catalog # | MBS1751960 |
Price | $315 |
Order / More Info | CD18 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Abramson, J. S., Mills, E. L., Sawyer, M. K., Regelmann, W. R., Nelson, J. D., Quie, P. G. Recurrent infections and delayed separation of the umbilical cord in an infant with abnormal phagocytic cell locomotion and oxidative response during particle phagocytosis. J. Pediat. 99: 887-894, 1981. 2. Akao, Y., Utsumi, K. R., Naito, K., Ueda, R., Takahashi, T., Yamada, K. Chromosomal assignments of genes coding for human leukocyte common antigen, T-200, and lymphocyte function-associated antigen 1, LFA-1 beta subunit. Somat. Cell Molec. Genet. 13: 273-278, 1987. 3. Entrez Gene: ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit). |