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Antigenic Specificity | Visfatin |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | 1ug/ul |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Visfatin, a newly identified adipocytokine, which is predominantly secreted from visceral adipose tissue both in humans and mice. Visfatin corresponds to a protein identified previously as pre-B cell colony-enhancing factor (PBEF). Visfatin exerted insulin-mimetic effects in cultured cells, various insulin- sensitive tissues such as liver, muscle, and fat, and lowered plasma glucose levels in mice. Mice heterozygous for a targeted mutation in the visfatin gene had modestly higher levels of plasma glucose relative to wild-type littermates. visfatin binds to and activates the insulin receptor. Which may lead to new insights into glucose homeostasis and/or new therapies for metabolic disorders such as diabetes. |
Immunogen | Immunogen: Ni-NTA purified truncated recombinant Visfatin expressed in E Coli strain BL21 (DE3) |
Other Names | [visfatin, partial; Visfatin; nicotinamide phosphoribosyltransferase; nicotinamide phosphoribosyltransferase; Visfatin], [NAMPT; PBEF1; PBEF1; NAMPTP1; visfatin] |
Gene, Accession # | Gene ID: 417707, NCBI: AEC22813.1 |
Catalog # | MBS418413 |
Price | $445 |
Order / More Info | Visfatin Antibody from MYBIOSOURCE INC. |
Product Specific References | 1.Jin S et.al J Biol Chem. 2005 Jul 1;280 (26):24698-705. 2.Antignani A, et.al Biochemistry. 2005 Mar 15;44 (10):4074-82. |