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Antigenic Specificity | Human IRAK1 / IRAK |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | ammonium sulfate precipitate |
Size | 0.2 mL |
Concentration | 0.25 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | IRAK1, an IRAK type protein kinase, is a signal transducer for the immune response Toll-like receptor and interleukin-1 (IL-1) receptor signaling cascades. IRAK1 is recruited to the IL-1 receptor, phosphorylated and progressively degraded in response to IL-1 induction. The protein also has the ability to autophosphorylate. IRAK1 is immediately downstream of the MyD88 adapter protein and immediately upstream of TRAF6. IRAK1 (-/-) mice have impaired responses to interleukin-18. |
Immunogen | Immunogen Description: KLH conjugated synthetic peptide selected from the C-terminal region of human IRAK1. |
Other Names | [IRAK1 / IRAK (C-Terminus) IHC-plus; IRAK1; IRAK-1; Pelle; Il1rak; IRAK; Pelle homolog; Human IRAK1; IRAK], [IRAK] |
Gene, Accession # | [IRAK1], Gene ID: 3654, NCBI: NP_001560.2, UniProt: P51617 |
Catalog # | MBS242591 |
Price | $530 |
Order / More Info | Human IRAK1 / IRAK Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |