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Antigenic Specificity | TRAIL (Human) |
Clone | RIK-2 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human TRAIL. Induces apoptosis in tumorigenic and transformed cell lines, involved in T cell mediated cytotoxicity, TRAIL ligand of cognate receptors induces NF-kappa-B signaling in a variety of cell types. TRAIL is a 30kDa protein known as TNF-related apoptosis inducing ligand, CD253, TNFSF10, or Apo-2L. It can be expressed as a cell surface (30kDa) and soluble ligand (19-20kDa) produced by megakaryocytes and platelets, monocytes, neutrophils, NK cells and activated T cells. This antigen is also expressed on tumor cells and transformed cell lines. TRAIL has been reported to induce apoptosis in tumor and transformed cell lines by a caspase-dependent process. This antibody is useful for flow cytometric staining and blocking studie |
Immunogen | Immunogen: Human TRAIL transfected mouse cell line. |
Other Names | [TRAIL], [TNFSF10; TNFSF10; TL2; APO2L; CD253; TRAIL; Apo-2L; TNLG6A; APO2L; TRAIL; Apo-2L; Protein TRAIL] |
Gene, Accession # | [Apo-2L; TNFSF 10; CD253], Gene ID: 8743, NCBI: P50591.1, UniProt: P50591 |
Catalog # | MBS565040 |
Price | $295 |
Order / More Info | TRAIL (Human) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |