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Antigenic Specificity | ZAP 70 (pTyr493) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (expected from sequence), rat (expected from sequence) |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti ZAP 70 (pTyr493) antibody recognizes ZAP 70, also known as Zeta-chain-associated protein kinase 70 when phosphorylated at tyrosine 493. ZAP70 is a member of the tyrosine kinase family. ZAP 70 plays a key role in the activation of T cells. ZAP 70 is phosphorylated at tyrosine 493 by Lck in response to T cell receptor stimulation (Wang et al. 2010). Phosphorylation of ZAP 70 at tyrosine 493 fully activates ZAP 70 leading to phosphorylation of downstream targets of the T cell activation pathway. |
Immunogen | Immunogen: Phospho specific-peptide corresponding to residues surrounding tyrosine 493 of human ZAP 70 |
Other Names | [ZAP 70 (pTyr493)], [ZAP70; ZAP70; SRK; STD; TZK; STCD; IMD48; ADMIO2; ZAP-70; SRK] |
Gene, Accession # | [ZAP70], Gene ID: 7535, NCBI: P43403.1, UniProt: P43403 |
Catalog # | MBS225325 |
Price | $375 |
Order / More Info | ZAP 70 (pTyr493) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |