TICAM2 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-TICAM2 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | TICAM2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mg |
| Concentration | 0.50-0.75 ug/ul in antibody stabilization buffer |
| Applications | Dot Blot (DB), ELISA (EIA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Affinity Purified TRIF-related adapter molecule Antibody. Functions as sorting adapter in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. Physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1; signaling is proposed to occur in early endosomes after endocytosis of TLR4. May also be involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB; however, reports are controversial. Involved in IL-18 signaling and is proposed to function as a sorting adaptor for MYD88 in IL-18 signaling during adaptive immune response. |
| Immunogen | Immunogen: Synthetic peptide corresponding to unique amino acid sequences on TRIF-related adapter molecule. Expression: Expressed in spleen, prostate, testis, uterus, small intestine, colon, peripheral blood leukocytes, heart, placenta, lung, liver, skeletal muscle, and pancreas Isoform 2 is ubiquitously expressed (at lower levels than isoform 1). |
| Other Names | [Putative NF-kappa-B-activating protein 502; TICAM2; TIR containing adapter molecule 2; TIR domain-containing adapter molecule 2; TIRAP3; TIRP; Toll-like receptor adaptor protein 3; Toll/interleukin-1 receptor domain-containing protein; TRAM; TRIF-related adapter molecule], [TICAM2; TIRAP3; TIRP; TRAM; TICAM-2; MyD88-4] |
| Gene, Accession # | [TICAM2], NCBI: AAO74498.1, UniProt: Q86XR7 |
| Catalog # | MBS540128 |
| Price | $425 |
| Order / More Info | TICAM2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies