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Antigenic Specificity | JMJD1B |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody will not cross-react with JMJD1A or JMJD1C. The jumonji domain containing 1B protein (JMJD1B) was originally discovered as a candidate for the myeloid leukemia tumor suppressor gene. Besides CD34+ cells and acute myeloid leukemia (AML) cell lines, JMJD1B mRNA is highly expressed in liver, heart, kidney, skeletal muscle, and placenta tissues. The JMJD1B gene is localized to a region of chromosome 5q31, which is frequently deleted in myeloid leukemias and myelodysplasias and expression of JMJD1B in a del(5q) cell line results in suppression of clonogenic growth suggesting that JMJD1B may function as a tumor suppressor. In contrast, JMJD1B gene copy number and mRNA expression level was increased in several non-small cell lung can |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 20 amino acid peptide from near the center of human JMJD1B. |
Other Names | [5qNCA, Lysine-specific demethylase 3B, KDM3B] |
Gene, Accession # | [JMJD1B], Gene ID: 51780, NCBI: EAW62141 |
Catalog # | MBS9402186 |
Price | $320 |
Order / More Info | JMJD1B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |