PDGFRA Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | PDGFRA |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Platelet derived growth factor (PDGF) family proteins exist as several disulphide-bonded, dimeric isoforms (PDGF AA, PDGF AB, PDGF BB, PDGF CC, and PDGF DD) that bind in a specific pattern to two closely related receptor tyrosine kinases, PDGF receptor alpha (PDGFRalpha) and PDGF receptor beta (PDGFRbeta). PDGFRalpha and PDGFRbeta share 75% to 85% sequence homology between their two intracellular kinase domains, while the kinase insert and carboxy-terminal tail regions display a lower level (27% to 28%) of homology (1). PDGFRalpha homodimers bind all PDGF isoforms except those containing PDGF D. PDGFRbeta homodimers bind PDGF BB and DD isoforms, as well as the PDGF AB heterodimer. The heteromeric PDGF receptor alpha/beta binds PDGF B, C, an |
| Immunogen | Immunogen: Recombinant protein of human PDGFRA Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [CD140A; MGC74795; PDGFR2; Rhe-PDGFRA] |
| Gene, Accession # | [PDGFRA], Gene ID: 5156, NCBI: NP_001334758.1, UniProt: P16234 |
| Catalog # | MBS8502453 |
| Price | $310 |
| Order / More Info | PDGFRA Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Deuel, T.F. et al. (1988) Biofactors 1, 213-217. 2. Bergsten, E. et al. (2001) Nat. Cell Biol. 3, 512-516. 3. Betsholtz, C. et al. (2001) Bioessays 23, 494-507. 4. Coughlin, S.R. et al. (1988) Prog. Clin. Biol. Res. 266, 39-45. 5. Ostman, A. and Heldin, C.H. (2001) Adv. Cancer Res. 80, 1-38. 6. Panayotou, G. et al. (1992) EMBO J. 11, 4261-4272. 7. Ramalingam, K. et al. (1995) Bioorg. Med. Chem. 3, 1263-1272. 8. Kashishian, A. et al. (1992) EMBO J. 11, 1373-1382. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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