Endoglin/CD105 (Angiogenesis Marker) Antibody from MYBIOSOURCE INC.

Search, find, compare suppliers for anti-Endoglin/CD105 (Angiogenesis Marker) antibody, protein, ELISA kits.

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Antigenic SpecificityEndoglin/CD105 (Angiogenesis Marker)
Clone[ENG/3269]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2b, kappa
Formatpurified
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA at 1mg/ml)
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) Paraffin
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DescriptionSpecificity: CD105/Endoglin is a Type I membrane glycoprotein located on cell surfaces and is part of the TGF-beta receptor complex. This protein has been found on endothelial cells, activated macrophages, fibroblasts, and smooth-muscle cells. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling. Its expression is regulated during heart development. CD105 is highly expressed in endothelial cells during tumor angiogenesis and inflammation, with weak or negative expression in vascular endothelium of normal tissues. Angiogenesis is a promising prognostic marker in a variety of tumors. Endoglin is a more specific and sensitive marker for tumor angiogenesis than CD31 or CD34, as it labels only newly-form
ImmunogenImmunogen: Recombinant human Endoglin protein fragment (aa74-251) (exact sequence is proprietary)
Other Names[CD105; END; Endoglin; Eng; HHT1; S-endoglin]
Gene, Accession #[ENG], Gene ID: 2022, NCBI: NP_000109.1, UniProt: P17813
Catalog #MBS4380857
Price$190, $340, $340
Order / More InfoEndoglin/CD105 (Angiogenesis Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesAltomonte, M., et al. 1996. Expression and structural features of Endoglin (CD105), a transforming growth factor 1 and 3 binding protein, in human melanoma. Br. J. Cancer 74: 1586-1591.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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