Phospho-TRAF2 (Ser11) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-TRAF2 (Ser11) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-TRAF2 (Ser11) antibody detects endogenous levels of TRAF2. Function: Regulates activation of NF-kappa-B and JNK and plays a central role in the regulation of cell survival and apoptosis. Required for normal antibody isotype switching from IgM to IgG. Has E3 ubiquitin-protein ligase activity and promotes 'Lys-63'-linked ubiquitination of target proteins, such as BIRC3, RIPK1 and TICAM1. Is an essential constituent of several E3 ubiquitin-protein ligase complexes, where it promotes the ubiquitination of target proteins by bringing them into contact with other E3 ubiquitin ligases. Regulates BIRC2 and BIRC3 protein levels by inhibiting their autoubiquitination and subsequent degradation; this does not depend on the TRAF2 R |
| Immunogen | Immunogen: A synthesized peptide derived from human TRAF2 around the phosphorylation site of Ser11. Subcellular Location: Cytoplasm. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Dog, Chicken Similarity: Pig (92%), Bovine (92%), Horse (92%), Sheep (92%), Dog (92%), Chicken (82%) |
| Other Names | [E3 ubiquitin-protein ligase TRAF2; MGC:45012; OTTHUMP00000022625; OTTHUMP00000064745; TNF receptor associated factor 2; TNF receptor-associated factor 2; TNF receptor-associated protein; TRAF 2; TRAF2; TRAF2_HUMAN; TRAP 3; TRAP; TRAP3; Tumor necrosis factor type 2 receptor associated protein 3; Tumor necrosis factor type 2 receptor-associated protein 3] |
| Gene, Accession # | [TRAF2], Gene ID: 7186, NCBI: NP_066961.2, UniProt: Q12933 |
| Catalog # | MBS9600756 |
| Price | $240, $280 |
| Order / More Info | Phospho-TRAF2 (Ser11) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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