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Antigenic Specificity | Mouse CDw199 |
Clone | [9B1] |
Host Species | Rat |
Reactive Species | n/a |
Isotype | IgG2a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 1.0mg/ml |
Applications | Flow cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rat anti Mouse CDw199 antibody, clone 9B1 detects mouse chemokine receptor 9 (CCR9), also known as CDw199. CCR9 is a seven transmembrane protein which is a member of the beta chemokines receptor family. CCR9 is expressed in thymus and small intestine, and mediates the recruitment and development of thymocytes in response to CCL25; the only known ligand of CCR9. CCR9 is an alternative co-receptor with CD4 for HIV infection, and has been implicated in adult T cell leukaemia. Two alternatively spliced transcript variants have been described. Clone 9B1 blocks CCL25-induced Ca2+ release, attenuating inflammation in a murine model of chronic ileitis when given in early disease stages. |
Immunogen | Immunogen: 25 amino acids from the amino terminal of murine CCR9, coupled to KLH. Fusion Partners: Spleen cells from immunised Lewis rat were fused with cells of the X63-Ag8.653 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Mouse |
Other Names | [C-C chemokine receptor type 9; C-C chemokine receptor type 9; C-C chemokine receptor type 9; C-C CKR-9; CC-CKR-9; CCR-9; chemokine C-C receptor 10; chemokine (C-C motif) receptor 9; Chemokine C-C receptor 10; CD_antigen: CDw199], [Ccr9; Ccr9; Cmkbr10; GPR-9-6; A130091K22Rik; Cmkbr10; C-C CKR-9; CC-CKR-9; CCR-9] |
Gene, Accession # | [CDw199], Gene ID: 12769, NCBI: NP_001160097.1, UniProt: Q9WUT7 |
Catalog # | MBS219354 |
Price | $335 |
Order / More Info | Mouse CDw199 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |