APE1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityAPE1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatProtein A purified
Size0.1 mL
Concentration100ug/100ul
ApplicationsPeptide ELISA (EIA), Western Blot (WB)
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DescriptionSpecificity: APE1 antibody detects endogenous levels of APE1protein. Not tested with other proteins. Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein
ImmunogenImmunogen: Synthetic peptide conjugated to KLH
Other Namesn/a
Gene, Accession #[APE1]
Catalog #MBS416248
Price$230
Order / More InfoAPE1 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesLiu,Y., Prasad,R., Beard,W.A.,et,al Coordination of steps in single-nucleotide base excision repair mediated by apurinic/apyrimidinic endonuclease 1 and DNA polymerase beta
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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