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Antigenic Specificity | ERBB2 (Center Y877) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human; predicted reactivity: mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.08 mL, 0.4 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This ERBB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 855-883 amino acids from the Central region of human ERBB2. Description: This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (p |
Immunogen | n/a |
Other Names | [Receptor tyrosine-protein kinase erbB-2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; CD340; ERBB2; HER2; MLN19; NEU; NGL] |
Gene, Accession # | [ERBB2], Gene ID: 2064, NCBI: NP_001005862.1, UniProt: P04626 |
Catalog # | MBS9217112 |
Price | $165, $370 |
Order / More Info | ERBB2 (Center Y877) Antibody from MYBIOSOURCE INC. |
Product Specific References | Geradts, J., et al. Cancer Invest. 28 (9):969-977 (2010). Zaoui, K., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (43):18517-18522 (2010). Oliveras, G., et al. Ann. N. Y. Acad. Sci. 1210, 86-92 (2010). Han, J.S., et al. Anticancer Res. 30 (9):3407-3412 (2010). Stackievicz, R., et al. Isr. Med. Assoc. J. 12 (5):290-295 (2010). |