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Antigenic Specificity | Choactase |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Choactase Polyclonal Antibody detects endogenous levels of Choactase protein. CHAT encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. CHAT product (choline O-acetyltransferase) is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in CHAT have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in CHAT are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for CHAT, and some of these variants have been shown to encode more than one isoform. |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human Choactase |
Other Names | [Rabbit Choactase; Choline O-acetyltransferase; CHOACTase; ChAT; Choline acetylase] |
Gene, Accession # | [CHAT], Gene ID: 1103, NCBI: P28329.4, UniProt: P28329 |
Catalog # | MBS9701698 |
Price | $130, $220, $325 |
Order / More Info | Choactase Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |