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Antigenic Specificity | Mouse CD27/TNFRSF7 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | IgG |
Format | unconjugated |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD27, also known as TNFRSF7, is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage, and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a type I transmembrane glycoprotein of about 55 kDa existing as disulfide-linked homodimer, CD27 has been shown to play roles in lymphoid proliferation, differentiation, and apoptosis.It has important role in generation of T cell immunity, and is an apparently robust marker for normal memory B cells. It is a T and B cell co-stimulatory molecule, the activity of CD27 is governed by its TNF-like ligand CD70 on lymphocytes and dendritic cells. The CD27-CD70 interaction is required for Th1 generation responses to differentiation sign |
Immunogen | Immunogen: Recombinant Mouse CD27 protein Buffer: This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD27 (rM CD27; NP 001028298.1; Met 1-Arg 182). |
Other Names | [CD27 antigen; CD27 antigen; CD27 antigen; CD27 molecule; CD27L receptor; T-cell activation antigen CD27; T14; Tumor necrosis factor receptor superfamily member 7; CD_antigen: CD27] |
Gene, Accession # | [CD27/TNFRSF7 ], Gene ID: 939 |
Catalog # | MBS2544482 |
Price | $215, $330, $500 |
Order / More Info | Mouse CD27/TNFRSF7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |