JNK1 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-JNK1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | JNK1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The stress-activated protein kinase/Jun-amino-terminal kinase SAPK/JNK is potently and preferentially activated by a variety of environmental stresses including UV and gamma radiation, ceramides, inflammatory cytokines, and in some instances, by growth factors and GPCR agonists (1-6). As with the other MAPKs, the core signaling unit is composed of a MAPKKK, typically MEKK1-MEKK4, or by one of the mixed lineage kinases (MLKs), which phosphorylate and activate MKK4/7. Upon activation, MKKs phosphorylate and activate the SAPK/JNK kinase (2). Stress signals are delivered to this cascade by small GTPases of the Rho family (Rac, Rho, cdc42) (3). Both Rac1 and cdc42 mediate the stimulation of MEKKs and MLKs (3). Alternatively, MKK4/7 can be activa |
| Immunogen | Immunogen: Recombinant protein of human JNK1 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [MAPK8; JNK; JNK1; JNK1A2; JNK21B1/2; PRKM8; SAPK1] |
| Gene, Accession # | [JNK1], Gene ID: 5599, NCBI: NP_001265476.1, UniProt: P45983 |
| Catalog # | MBS8501695 |
| Price | $310 |
| Order / More Info | JNK1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Davis, R.J. (1999) Biochem Soc Symp 64, 1-12. 2. Ichijo, H. (1999) Oncogene 18, 6087-93. 3. Kyriakis, J.M. and Avruch, J. (2001) Physiol Rev 81, 807-69. 4. Kyriakis, J.M. (1999) J Biol Chem 274, 5259-62. 5. Leppa, S. and Bohmann, D. (1999) Oncogene 18, 6158-62. 6. Whitmarsh, A.J. and Davis, R.J. (1998) Trends Biochem Sci 23, 481-5. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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