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Antigenic Specificity | APO-E |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | APO-E Antibody: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E (APO-E), a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. Defects in APO-E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. |
Immunogen | Immunogen: APO-E antibody was raised against a 19 amino acid peptide near the carboxy terminus of human APO-E. Buffer: APO-E Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [APO-E; AD2; LPG; LDLCQ5; Apolipoprotein E; Apo-E; apolipoprotein E], [APOE; APOE; AD2; LPG; APO-E; LDLCQ5; Apo-E] |
Gene, Accession # | [APOE], Gene ID: 348, NCBI: NP_000032, UniProt: P02649 |
Catalog # | MBS153474 |
Price | $375 |
Order / More Info | APO-E Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |