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Antigenic Specificity | NEURL2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: NEURL2 antibody detects endogenous levels of total NEURL2. Function: Plays an important role in the process of myofiber differentiation and maturation. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. Probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma (By similarity).Subunit Structure: Probable component the ECS(NEURL2) E3 ubiquitin-protein ligase complex consisting of ELOB/Elongin B, ELOC/El |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cytoplasm. Tissue Specificity: Expressed specifically in skeletal and cardiac muscles. Predicted Cross Reactivity: Bovine, Horse, Sheep, Rabbit, Dog Similarity: Bovine (100%), Horse (91%), Sheep (100%), Rabbit (90%), Dog (91%) |
Other Names | [NEUL2_HUMAN; Neuralized like protein 2; Neuralized-like protein 2; NEURL2] |
Gene, Accession # | [NEURL2], Gene ID: 140825, NCBI: NP_001265464.1, UniProt: Q9BR09 |
Catalog # | MBS9605681 |
Price | $240, $280 |
Order / More Info | NEURL2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |