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Antigenic Specificity | SPHK1 - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SPHK1 |
Other Names | [sphingosine kinase 1 isoform 3; Sphingosine kinase 1; sphingosine kinase 1; sphingosine kinase 1] |
Gene, Accession # | [SPHK1], Gene ID: 8877, NCBI: NP_001136073.1, UniProt: Q9NYA1 |
Catalog # | MBS3221508 |
Price | $335 |
Order / More Info | SPHK1 - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |