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Antigenic Specificity | AEG1 (pS568) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, bovine |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes phosphospecific AEG1at phosphorylated Ser568. It does not recognize non-phosphspecific site Ser568. This antibody reacts with human, mouse and rat origins. The other species are not tested. AEG1 (Astrocyte elevated gene 1), also called MTDH (Metadherin), or L LYsine-RIch CEACAM1 co-isolated (LYRIC), is 582 aa single transmembrane domain (TMD) protein. It is widely expressed and highly conserved between species. It is recruited during the maturation of the tight junction complex and co-localizes with tight junction proteins ZO-1 and occludin in polarized epithelial cells. AEG-1 is involved in several crucial aspects of tumor progression, including transformation, evasion of apoptosis, invasion, metastasis, and chemor |
Immunogen | n/a |
Other Names | [Metadherin; 3D3; AEG1; AEG-1; LYRIC; LYRIC/3D3], [MTDH; MTDH; 3D3; AEG1; AEG-1; LYRIC; LYRIC/3D3; AEG1; LYRIC; AEG-1] |
Gene, Accession # | [AEG1], Gene ID: 92140, NCBI: AAO65771.1 |
Catalog # | MBS460566 |
Price | $285 |
Order / More Info | AEG1 (pS568) Antibody from MYBIOSOURCE INC. |
Product Specific References | Sutherland HG, et al. 3D3/lyric: a novel transmembrane protein of the endoplasmic reticulum and nuclear envelope, which is also present in the nucleolus. Exp Cell Res. 2004 Mar 10;294 (1):94-105. |