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Antigenic Specificity | Human CD11b |
Clone | [OKM1] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b,k |
Format | Protein A purified |
Size | 0.1 mg, 0.5 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: ITGAM(Integrin Alpha-M), also called CD11B or Mo1 ALPHA SUBUNIT(MO1A), is one protein subunit that forms the heterodimeric integrin alpha-M beta-2(alphaMbeta2) molecule. A major surface antigen family on human leukocytes includes complement receptor type 3(CR3A; also called ITGAM, Mac1, or Mo1), lymphocyte function-associated(LFA) antigen type 1(ITGAL), and p150, 95(ITGAX). By in situ hybridization, Corbi et al.(1988) demonstrated that the genes encoding the alpha subunits of LFA1(ITGAL), Mac1, and p150, 95(ITGAX), all of which are involved in leukocyte adhesion, constitute a cluster on 16p13.1-p11. Callen et al.(1991) narrowed the assignment to 16p11.2. Inflammation plays an essential role in the initiation and progression of |
Immunogen | Immunogen: Human PBMC. Subcellular Localization: Membrane; Single-pass type I membrane protein. Sequence Similarities: Belongs to the integrin alpha chain family. Tissue Specificity: Predominantly expressed in monocytes and granulocytes. |
Other Names | [Integrin alpha-M; CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; CD11b; Itgam], [Itgam] |
Gene, Accession # | [CD11b], Gene ID: 16409, NCBI: P05555.2, UniProt: P05555 |
Catalog # | MBS178875 |
Price | $120, $245 |
Order / More Info | Human CD11b Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |