ITGA8 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityITGA8
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: ITGA8 antibody detects endogenous levels of total ITGA8. Function: Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGFB1, TGFB3 and VTN. NPNT is probably its functional ligand in kidney genesis. Neuronal receptor for TNC it mediates cell-cell interactions and regulates neurite outgrowth of sensory and motor neurons.Subunit Structure: Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of a heavy and a light chain linked by a disulfide bond. Alpha-8 associates with beta-1.Similarity: Belongs to the
ImmunogenImmunogen: A synthesized peptide derived from human ITGA8 Subcellular Location: Membrane. Tissue Specificity: Expressed in mesenchymal cells, including alveolar myofibroblasts, kidney mesangial cells and hepatic stellar cells and vascular and visceral smooth muscle (at protein level).
Other Names[Integrin alpha 8; Integrin alpha-8 heavy chain; Integrin alpha-8 light chain; ITA8_HUMAN; ITGA 8; ITGA8]
Gene, Accession #[ITGA8], Gene ID: 8516, NCBI: NP_003629.2, UniProt: P53708
Catalog #MBS9609310
Price$240, $280
Order / More InfoITGA8 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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