Pyrralin (Advanced Glycation End Product) Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | Pyrralin (Advanced Glycation End Product) |
| Clone | polyclonal |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | biotin conjugate |
| Size | 0.02 mg |
| Concentration | 0.25 mg/ml |
| Applications | Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody is suitable for the detection of bound and free pyrraline in tissues and tissue extracts. Long-term incubation of proteins with glucose leads, through Schiff's base and Amadori rearrangement products, to the formation of advanced glycation end products (AGE) which are characterized by fluorescence, brown color and inter- and intra-molecular cross-linking. Recent immunological studies using anti-AGE antibodies demonstrated the presence of AGE in (i) human lens, (ii) renal proximal tubules in patients with diabetic nephropathy and chronic renal failure, (iii) atherosclerotic lesions of arterial walls, (iv) beta2-microglobulin of carpal tunnel amyloid fibril deposits in patients with hemodialysis-related amyloidosis and (v) brain |
| Immunogen | Immunogen: Pyrraline-HSA |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS397332 |
| Price | $1475 |
| Order / More Info | Pyrralin (Advanced Glycation End Product) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Horiuchi S., Araki N., and Morino Y. (1991) Immunological approach to characterize advanced glycation end products of the Maillard reaction: Evidence for the presence of a common stucture. J. Biol. Chem. 266; 7329-7332. 2. Miyata S., and Monnier V. (1992): Immunohistochemical detection of advanced glycosylation end products in diabetic tissues using monoclonal antibody to pyrraline, J. Clin. Invest. 89(4): 1102-1112. 3. Smith M.A., Taneda S., Richey P.L., Miyata S., Yan S.D., Stren D., Sayre L.M., Monnier V.M., Perry G. (1994): Advanced Maillard reaction end products are associated with Alzheimer disease pathology. Proc. Natl. Acad. Sci. USA91(12): 5710-5714. 4. Odetti P., Angelini G., Dapino D., Zaccheo D., Garibaldi S., Dagna-Bricarelli F., Piombo G., Perry G., Smith M., Traverso N., Tabaton M.(1998): Early glycoxidation damage in brains from Down's syndrome. Biochem. Biophys. Res. Commun. 243(3): 849-851. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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