Human Low-density lipoprotein receptor-related protein 6 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Human Low-density lipoprotein receptor-related protein 6 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Required for posterior patterning of the epiblast during gastrulation (By similarity). |
| Immunogen | Immunogen: Recombinant human Low-density lipoprotein receptor-related protein 6 protein (20-150aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-17982 / sc-17984 / sc-134462 / sc-15399 |
| Other Names | [LRP-6; LRP6], [LRP6; LRP6; ADCAD2; LRP-6] |
| Gene, Accession # | [LRP6], Gene ID: 4040, NCBI: NP_002327.2, UniProt: O75581 |
| Catalog # | MBS1495105 |
| Price | $120, $160 |
| Order / More Info | Human Low-density lipoprotein receptor-related protein 6 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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