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Antigenic Specificity | ADIPOQ |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 19-104 of human ADIPOQ (NP 004788.1). |
Other Names | [ACDC; ADPN; APM1; APM-1; GBP28; ACRP30; ADIPQTL1] |
Gene, Accession # | [ADIPOQ], Gene ID: 9370, NCBI: NP_001171271.1, UniProt: Q15848 |
Catalog # | MBS8544975 |
Price | $280 |
Order / More Info | ADIPOQ Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |