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Antigenic Specificity | CC2D1A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CC2D1A antibody detects endogenous levels of total CC2D1A. Function: Transcription factor that binds specifically to the DRE (dual repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell. Performs essential function in controlling functional maturation of synapses (By similarity). Plays distinct roles depending on its localization. When cytoplasmic, acts as a scaffold protein in the PI3K/PDK1/AKT pathway. Repressor of HTR1A when nuclear. In the centrosome, regu |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cytoplasm. Nucleus. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Dog Similarity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Dog (100%) |
Other Names | [Akt kinase interacting protein 1; Coiled coil and C2 domain containing 1A; Coiled coil and C2 domain containing protein 1A; Five repressor element under dual repression binding protein 1; FLJ20241; FLJ41160; FRE under dual repression binding protein 1; FREUD 1; Freud 1/Aki1; Mental retardation, nonsyndromic, autosomal recessive, 3; MRT3; Putative NF kappa B activating protein 023N; Putative NF kappa B activating protein] |
Gene, Accession # | [CC2D1A], Gene ID: 54862, NCBI: NP_060191.3, UniProt: Q6P1N0 |
Catalog # | MBS9604102 |
Price | $240, $280 |
Order / More Info | CC2D1A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |