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Antigenic Specificity | SOX10 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: SOX10 antibody detects endogenous levels of total SOX10. Function: Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3 (PubMed:21965087).Subunit Structure: Monomer. Interacts with ARMCX3 at the mitochondrial outer membrane surface. Interacts with PAX3 (PubMed:21965087). |
Immunogen | Immunogen: A synthesized peptide derived from human SOX10 Subcellular Location: Cytoplasm. Nucleus. Tissue Specificity: Expressed in fetal brain and in adult brain, heart, small intestine and colon. Predicted Cross Reactivity: Pig, Bovine, Sheep, Rabbit, Dog, Chicken Similarity: Pig (100%), Bovine (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (83%) |
Other Names | [DOM; DOM; Dominant megacolon mouse human homolog of; MGC15649; PCWH; SOX 10; SOX10; SOX10_HUMAN; SRY (sex determining region Y) box 10; SRY (sex determining region Y) box 10; SRY box 10; SRY box containing gene 10; SRY related HMG box gene 10; SRY related HMG box gene 10; Transcription factor SOX 10; Transcription factor SOX-10; WS2E; WS4; WS4C] |
Gene, Accession # | [SOX10], Gene ID: 6663, NCBI: NP_008872.1, UniProt: P56693 |
Catalog # | MBS9608496 |
Price | $240, $280 |
Order / More Info | SOX10 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |