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Antigenic Specificity | Human Dual specificity mitogen-activated protein kinase kinase 3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | caprylic acid ammonium sulfate precipitate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38.This protein is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncog |
Immunogen | Immunogen: Recombinant human Dual specificity mitogen-activated protein kinase kinase 3 protein |
Other Names | [MAPK/ERK kinase 3 MAP2K3 MEK3; MKK3; PRKMK3; SKK2] |
Gene, Accession # | Gene ID: 5606, NCBI: NP_001303261.1, UniProt: P46734 |
Catalog # | MBS7005370 |
Price | $160, $235 |
Order / More Info | Human Dual specificity mitogen-activated protein kinase kinase 3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |