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Antigenic Specificity | (Mouse) Wdr5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (predicted reactivity: rat) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This Mouse Wdr5 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the region of mouse Wdr5. Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation (By similarity). |
Immunogen | n/a |
Other Names | [WD repeat-containing protein 5; BMP2-induced 3-kb gene protein; WD repeat-containing protein BIG-3; Wdr5; Big; Big3] |
Gene, Accession # | [Wdr5], Gene ID: 140858, NCBI: NP_543124.1, UniProt: P61965 |
Catalog # | MBS9210774 |
Price | $165, $370 |
Order / More Info | (Mouse) Wdr5 Antibody from MYBIOSOURCE INC. |
Product Specific References | Gori F.,et al.J. Biol. Chem. 276:46515-46522(2001). Carninci P.,et al.Science 309:1559-1563(2005). Jiang H.,et al.Cell 144:513-525(2011). Yang Y.J.,et al.Cell 151:1097-1112(2012). Diao Y.,et al.Cell Stem Cell 11:231-241(2012). |