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Antigenic Specificity | Neural Cell Adhesion Molecule L1 |
Clone | [9H148] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a |
Format | Protein G purified |
Size | 100 tests |
Concentration | 0.025 mg/ml |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes the mouse Neural Cell Adhesion Molecule L1. The Neural Cell Adhesion Molecule L1 (NCAM-L1) is an Immunoglobulin superfamily (IgSF) adhesion molecule critical for neural development. NCAM-L1 binds homophilically and heterophilically with adhesion molecules including Axonin-1, CD9, Neurocan, and Integrins. Mutations of the gene encoding NCAM-L1 are associated with a subset of X-linked mental retardation syndromes, schizophrenia, and other neurological disorders. Cancer cells can proteolytically cleave NCAM-L1, releasing the soluble ectodomain. Within the ECD, human NCAM-L1 shares 86% and 87% aa identity with mouse and rat NCAM-L1, respectively. |
Immunogen | Immunogen: Mouse cerebellum-derived partially purified Neural Cell Adhesion Molecule L1. |
Other Names | Neural Cell Adhesion Molecule L1 (L1CAM, L1 cell adhesion molecule, CAML1, CD171, HSAS, HSAS1, MASA, MIC5, N-CAML1, N-CAM L1, S10, SPG1) (PE) |
Gene, Accession # | Gene ID: 3897, NCBI: NP_076493.1, UniProt: P32004 |
Catalog # | MBS608049 |
Price | $655 |
Order / More Info | Neural Cell Adhesion Molecule L1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |