Edit |   |
---|---|
Antigenic Specificity | TL1A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This polyclonal antibody will not cross-react with TL1. TL1A Antibody: Members in the TNF and its receptor superfamilies regulate immune responses and induce apoptosis. DR3 (also termed Wsl-1, Apo-3, TRAMP, and LARD) is preferentially expressed by T lymphocytes and upregulated during T cell activation. The ligand for DR3 was recently identified and designated TL1A. TL1A also binds decoy receptor DcR3/TR6, which is expressed in several lung and colon carcinomas and in some normal tissues. TL1A induces apoptosis and NF-κB activation in DR3 expressing cells, which is antagonized by DcR3. TL1A is upregulated by proinflammatory cytokines TNF and IL-1. TL1A is a longer variant of TL1 (also called VEGI). |
Immunogen | Immunogen: TL1A antibody was raised against a peptide corresponding to 14 amino acids near the amino terminus of human TL1A. Buffer: TL1A Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [TL1A; TL1; TL1A; VEGI; VEGI192A; TL1; Tumor necrosis factor ligand superfamily member 15; TNF ligand-related molecule 1; tumor necrosis factor (ligand) superfamily, member 15], [TNFSF15; TNFSF15; TL1; TL1A; VEGI; VEGI192A; TL1; VEGI] |
Gene, Accession # | [TNFSF15], Gene ID: 9966, NCBI: AAM77366, UniProt: O95150 |
Catalog # | MBS150585 |
Price | $375 |
Order / More Info | TL1A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |