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Antigenic Specificity | TAB2 (C-term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This TAB2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 646-680 amino acids from the C-terminal region of human TAB2. Adapter linking MAP3K7/TAK1 and TRAF6. Promotes MAP3K7 activation in the IL1 signaling pathway. The binding of 'Lys-63'- linked polyubiquitin chains to TAB2 promotes autophosphorylation of MAP3K7 at 'Thr-187'. Involved in heart development. |
Immunogen | n/a |
Other Names | [TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; Mitogen-activated protein kinase kinase kinase 7-interacting protein 2; TAK1-binding protein 2; TAB-2; TGF-beta-activated kinase 1-binding protein 2; TAB2; KIAA0733; MAP3K7IP2] |
Gene, Accession # | [TAB2], Gene ID: 23118, NCBI: NP_001278963.1, UniProt: Q9NYJ8 |
Catalog # | MBS9206807 |
Price | $165, $370 |
Order / More Info | TAB2 (C-term) Antibody from MYBIOSOURCE INC. |
Product Specific References | Takaesu G.,et al.Mol. Cell 5:649-658(2000). Nagase T.,et al.DNA Res. 5:277-286(1998). Nakajima D.,et al.DNA Res. 9:99-106(2002). Ota T.,et al.Nat. Genet. 36:40-45(2004). Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases. |