HAAO Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | HAAO |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | HAAO Antibody: HAAO (3-Hydroxyanthranilate 3, 4-dioxygenase) is a monomeric cytosolic protein of the family of intramolecular dioxygenases containing non-heme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is present in low amounts in the central nervous system. This enzyme participates in tryptophan metabolism. It employs one cofactor, iron. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurological and inflammatory disorders. HAAO has been suggested to play a role in |
| Immunogen | Immunogen: HAAO antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human HAAO. Buffer: HAAO Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [HAAO; HAO; 3-HAO; 3-hydroxyanthranilate 3; 4-dioxygenase; 3-hydroxyanthranilate oxygenase; 3-hydroxyanthranilate 3,4-dioxygenase], [HAAO; HAAO; HAO; 3-HAO] |
| Gene, Accession # | [HAAO], Gene ID: 23498, NCBI: NP_036337, UniProt: P46952 |
| Catalog # | MBS150662 |
| Price | $375 |
| Order / More Info | HAAO Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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