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Antigenic Specificity | HOIL-1L/RBCK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. predicted: mouse |
Isotype | n/a |
Format | Protein A purified |
Size | 0.025 mg, 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RBCK1 (RanBP-type and C3HC4-type zinc finger containing 1) is a transcription factor belonging to the RING-IBR protein family. It shuttles between the nucleus and cytoplasm, possessing both the nuclear export and localization signals within its amino acid sequence. RBCK1 deficiency causes polyglucosan storage myopathy associated with progressive muscle weakness and cardiomyopathy. RBCK1 negatively regulates the cellular antiviral response. RBCK1 regulates cell cycle progression and proliferation of ERalpha (estrogen receptor alpha)-positive breast cancer cells by supporting transcription of ERalpha and cyclin B1. |
Immunogen | Immunogen Information: A partial length recombinant HOIL-1L/RBCK1 protein (amino acids 121-333) was used as the immunogen for this antibody. |
Other Names | [RBCK1; C20orf18; RNF54; UBCE7IP3; XAP3; XAP4; HBV-associated factor 4; HOIL-1; Heme-oxidized IRP2 ubiquitin ligase 1; Hepatitis B virus X-associated protein 4; RING finger protein 54; Ubiquitin-conjugating enzyme 7-interacting protein 3; to HOIL-1L/RBCK1; HOIL-1L/RBCK1; HOIL-1L/RBCK1], [RBCK1; RBCK1; XAP3; XAP4; HOIL1; PBMEI; PGBM1; RBCK2; RNF54; HOIL-1; ZRANB4; C20orf18; UBCE7IP3; C20orf18; RNF54; UBCE7IP3; XAP3; XAP4; HOIL-1] |
Gene, Accession # | [HOIL-1L/RBCK1], Gene ID: 10616, NCBI: Q9BYM8.2, UniProt: Q9BYM8 |
Catalog # | MBS668676 |
Price | $140, $270 |
Order / More Info | HOIL-1L/RBCK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |