c-Abl (Tyr-245), phospho-specific Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | c-Abl (Tyr-245), phospho-specific |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat, mouse |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA, Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody was cross-adsorbed to phospho-tyrosine coupled to agarose then affinity purified using phosphoc- Abl (Tyr-245) peptide (without carrier). On SDS-PAGE immunoblots of K-562 treated with pervanadate, the antibody detects a 145 kDa* protein corresponding to c- Abl and a 210 kDa band corresponding to BCR-Abl. In addition, this antibody detects a 145 kDa band in Jurkat cells treated with pervanadate. The c-Abl proto-oncogene encodes a nonreceptor type protein tyrosine kinase that is widely expressed and is distributed in both the nucleus and the cytoplasm of cells. It has been implicated in regulation of cell proliferation, differentiation, apoptosis, cell adhesion, and stress response. A variety of stimuli activate c-Abl kinase inc |
| Immunogen | Immunogen: Phospho-c-Abl (Tyr-245) synthetic peptide (coupled to KLH) corresponding to amino acid residues around tyrosine 245 of human c- Abl. This peptide sequence has high homology to the conserved site in rat and mouse c-Abl, as well as in viral Abl and BCR-Abl fusion protein. |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS472013 |
| Price | $385 |
| Order / More Info | c-Abl (Tyr-245), phospho-specific Antibody from MYBIOSOURCE INC. |
| Product Specific References | • Brasher, B.B. et al. (2000) J. Biol. Chem. 275:35631.• Pluk, H. et al. (2002) Cell 108:247.• Van Etten, R.A. et al. (1999) Trends Cell. Biol. 9:179. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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