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Antigenic Specificity | ZFP36L2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mg |
Concentration | 0.5 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Overview: mRNA-binding protein that plays a key role in self-renewal of erythroid cells in response to glucocorticoids. Specifically binds to the AU-rich element (ARE) in the 3'-UTR of target mRNAs, promoting their deadenylation and degradation (PubMed:14981510). Specifically expressed in burst-forming unit-erythroid (BFU-E) progenitors in response to glucocorticoids and acts as a negative regulator of erythroid cell differentiation: promotes self-renewal of erythroid cells by binding mRNAs that are induced or highly expressed during terminal erythroid differentiation and promotes their degradation, preventing erythroid cell differentiation. Down-regulated during erythroid differentiation from the BFU-E stage, stabilizing mRNAs required for |
Immunogen | Immunogen: Synthetic peptide taken within amino acid reigon 350-400 on human Zinc finger protein 36, C3H1 type-like 2. Conjugation: Unconjugated |
Other Names | [Affinity Purified Zinc finger protein 36, C3H1 type-like 2; BRF2; Butyrate response factor 2; C3H1 type-like 2; EGF response factor 2; ERF 2; Protein TIS11D; RNF162C; TIS11D; ZFP36 like 2; ZFP36 ring finger protein like 2; Zinc finger protein 36; Zinc finger protein 36, C3H type like 1; zinc finger protein 36, C3H type like 2] |
Gene, Accession # | [ZFP36L2], Gene ID: 678, NCBI: NP_008818.3, UniProt: P47974 |
Catalog # | MBS5400849 |
Price | $390 |
Order / More Info | ZFP36L2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |