ZFP36L2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityZFP36L2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatantigen affinity purified
Size0.1 mg
Concentration0.5 ug/ul in antibody stabilization buffer
ApplicationsELISA (EIA), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
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DescriptionOverview: mRNA-binding protein that plays a key role in self-renewal of erythroid cells in response to glucocorticoids. Specifically binds to the AU-rich element (ARE) in the 3'-UTR of target mRNAs, promoting their deadenylation and degradation (PubMed:14981510). Specifically expressed in burst-forming unit-erythroid (BFU-E) progenitors in response to glucocorticoids and acts as a negative regulator of erythroid cell differentiation: promotes self-renewal of erythroid cells by binding mRNAs that are induced or highly expressed during terminal erythroid differentiation and promotes their degradation, preventing erythroid cell differentiation. Down-regulated during erythroid differentiation from the BFU-E stage, stabilizing mRNAs required for
ImmunogenImmunogen: Synthetic peptide taken within amino acid reigon 350-400 on human Zinc finger protein 36, C3H1 type-like 2. Conjugation: Unconjugated
Other Names[Affinity Purified Zinc finger protein 36, C3H1 type-like 2; BRF2; Butyrate response factor 2; C3H1 type-like 2; EGF response factor 2; ERF 2; Protein TIS11D; RNF162C; TIS11D; ZFP36 like 2; ZFP36 ring finger protein like 2; Zinc finger protein 36; Zinc finger protein 36, C3H type like 1; zinc finger protein 36, C3H type like 2]
Gene, Accession #[ZFP36L2], Gene ID: 678, NCBI: NP_008818.3, UniProt: P47974
Catalog #MBS5400849
Price$390
Order / More InfoZFP36L2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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