Sirt1 Protein (Human) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Sirt1 Protein (Human) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Sirt1 Protein (Human) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | immunoaffinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC), Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Sirtuin 1 (Sirt 1) is encoded by a gene that encodes a number of the sirtuin-like proteins, all homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain. Yeast sirtuin proteins are known to regulate epigenetic gene silencing, suppress recombination of DNA and repressess rDNA transcription by the RNA pol. Studies suggest that the human sirtuins regulate apoptosis by impairing proapoptotic ability and modulating cell senescence. They regulate muscle differentiation by deacetylating key proteins. They also deacetylate the following: 'Lys-382' of p53/TP53, TAF1B, 'Lys-266' of SUV39H1 (leading to its activation), 'Lys-26' of HIST1H1E, APEX1 at 'Lys-6' and 'Lys-7' and 'Lys-16' of histone H4 (in |
| Immunogen | Immunogen: Synthetic Peptide near C terminal of human Sirt 1 |
| Other Names | [NAD-dependent deacetylase sirtuin-1; hSIRT1; SIR2-like protein 1; hSIR2; SIRT1; SIR2L1], [SIRT1; SIRT1; SIR2L1; SIR2L1; hSIRT1; hSIR2; 75SirT1] |
| Gene, Accession # | Gene ID: 23411, NCBI: NP_001135970.1, UniProt: Q96EB6 |
| Catalog # | MBS395900 |
| Price | $340 |
| Order / More Info | Sirt1 Protein (Human) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies