c-Met (Phospho-Tyr1003) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-c-Met (Phospho-Tyr1003) antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | c-Met (Phospho-Tyr1003) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1.0 mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody detects endogenous level of c-Met only when phosphorylated at tyrosine 1003. Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Usatyuk PV, et al. (2014)J Biol Chem. Asiedu MK, et al. (2014) Oncogene 33, 1316-24. Dulak AM, et al. (2011) Oncogene 30, |
| Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of tyrosine 1003 (V-D-Y(p)-R-A) derived from Human c-Met. |
| Other Names | [HGF receptor; HGF-SF receptor; Hepatocyte growth factor receptor precursor; Hepatocyte growth factor receptor precursor; Met proto-oncogene tyros] |
| Gene, Accession # | [c-Met], Gene ID: 4233, NCBI: NP_000236.2, UniProt: P08581 |
| Catalog # | MBS9405898 |
| Price | $200, $255 |
| Order / More Info | c-Met (Phospho-Tyr1003) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies