Mouse CD184 (N-TERMINAL) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse CD184 (N-TERMINAL) |
| Clone | polyclonal |
| Host Species | Goat |
| Reactive Species | Xenopus |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | IgG concentration 1.0mg/ml |
| Applications | ELISA (EIA), Immunohistology Paraffin, Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This item recognises an epitope within the N-terminal (NT) region of mouse CD184, otherwise known as CXCR4 (C-X-C chemokine receptor type 4), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, ubiquitously expressed in blood and tissue cells, which acts as a specific receptor for the chemokine SDF-1 (Stromal cell-derived factor 1).. . Interaction of CD184 with SDF-1 mediates the chemotaxis of progenitor and mature blood cells, and is critical for B-lymphopoiesis and myelopoiesis. CD184 . is a major co-receptor for infection by T-cell tropic strains of HIV1, and also a primary receptor for some HIV2 isolates.. . This item is reported as suitable for use in immunocytochemistry on mouse spleen leucocytes. |
| Immunogen | Immunogen: Synthetic peptide YSEEVGSGDYDSNKEPCFRDENVHFNR corresponding to amino acids 14-40 within the N-terminal region of mouse CD184. Histology Positive Control Tissue: Spleen Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antiserum to mouse CD184 (NT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography. Target Species: Mouse |
| Other Names | [C-X-C chemokine receptor type 4; C-X-C chemokine receptor type 4; C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; SDF-1 receptor; chemokine (C-X-C) receptor 4; chemokine receptor 4; fusin; leukocyte-derived seven transmembrane domain receptor; leukocyte-expressed seven-transmembrane-domain; pre-B-cell-derived chemokine receptor; stromal cell-derived factor 1 receptor; chemokine (C-X-C motif) receptor 4; Fusin; Leukocyte-derived seven transmembrane domain receptor; LESTR; Pre-B-cell-derived chemokine receptor; PB-CKR; Stromal cell-derived factor 1 receptor; SDF-1 receptor; CD_antigen: CD184], [Cxcr4; Cxcr4; CD184; LESTR; Sdf1r; Cmkar4; PB-CKR; b2b220Clo; PBSF/SDF-1; Cmkar4; Lestr; Sdf1r; CXC-R4; CXCR-4; LESTR; PB-CKR; SDF-1 receptor] |
| Gene, Accession # | [CD184], Gene ID: 12767, NCBI: NP_034041.2, UniProt: P70658 |
| Catalog # | MBS223913 |
| Price | $470 |
| Order / More Info | Mouse CD184 (N-TERMINAL) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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