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Antigenic Specificity | TYR (Center), 176-205 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This TYR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-205 amino acids from the Central region of human TYR. TYR catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The protein has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this protein result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. |
Immunogen | n/a |
Other Names | [Tyrosinase; LB24-AB; Monophenol monooxygenase; SK29-AB; Tumor rejection antigen AB; TYR] |
Gene, Accession # | [TYR], Gene ID: 7299, NCBI: NP_000363.1, UniProt: P14679 |
Catalog # | MBS9210480 |
Price | $165, $370 |
Order / More Info | TYR (Center), 176-205 Antibody from MYBIOSOURCE INC. |
Product Specific References | Ostankovitch,M. J. Immunol. 182 (8), 4830-4835 (2009) Chintamaneni,C.D. Proc. Natl. Acad. Sci. U.S.A. 88 (12), 5272-5276 (1991) |