Edit |   |
---|---|
Antigenic Specificity | Myc |
Clone | [PMYCSHG] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg, 0.2 mg, 0.5 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunoprecipitation (IP) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Monoclonal antibodies are produced by immunizing mouse with synthetic peptide (EQKLISEEDL) coupled to KLH. Introduction: c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of c-Myc have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. |
Immunogen | n/a |
Other Names | [Myc; Myc, Mouse; MYC; CMYC; C-MYS; V-MYC; P64], [Amvgp1] |
Gene, Accession # | [Myc], Gene ID: 1491913, NCBI: NP_955602.1 |
Catalog # | MBS140119 |
Price | $230, $350, $695 |
Order / More Info | Myc Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |