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Antigenic Specificity | ACTN4 (N-term), 192-220 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine, chicken, mouse, rat) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This ACTN4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-220 amino acids from the N-terminal region of human ACTN4. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin |
Immunogen | n/a |
Other Names | [Alpha-actinin-4; F-actin cross-linking protein; Non-muscle alpha-actinin 4; ACTN4] |
Gene, Accession # | [ACTN4], Gene ID: 81, NCBI: NP_004915.2, UniProt: O43707 |
Catalog # | MBS9204403 |
Price | $165, $370 |
Order / More Info | ACTN4 (N-term), 192-220 Antibody from MYBIOSOURCE INC. |
Product Specific References | Kikuchi,S., Clin. Cancer Res. 14 (17), 5348-5356 (2008) Barbolina,M.V., Lab. Invest. 88 (6), 602-614 (2008) Kimura,M., Intern. Med. 47 (12), 1099-1106 (2008) |