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Antigenic Specificity | EHMT2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: EHMT2 antibody detects endogenous levels of total EHMT2. Description: G9a, also known as Euchromatic histone-lysine N-methyltransferase 2 (EHMT2), is a member of a family of histone lysine methyltransferases, each of which contains a conserved catalytic SET domain originally identified in Drosophila Su[var]3-9, Enhancer of zeste, and Trithorax proteins (1). Recombinant G9a can mono-, di-and tri-methylate histone H3 on Lys9 and Lys27 in vitro (1, 2). However, in vivo G9a forms a complex with GLP, a G9a-related histone methyltransferase, and together these proteins function as the major euchromatic histone H3 Lys9 mono-and di-methyltransferases, creating transcriptionally repressive marks that facilitate gene silencing (3, 4). G9 |
Immunogen | Immunogen: A synthesized peptide derived from human EHMT2 Subcellular Location: Nucleus. Chromosome. Associates with euchromatic regions. Does not associate with heterochromatin. Tissue Specificity: Expressed in all tissues examined, with high levels in fetal liver, thymus, lymph node, spleen and peripheral blood leukocytes and lower level in bone marrow. |
Other Names | [Ankyrin repeat containing protein; Bat 8; Bat8; C6orf30; DKFZp686H08213; EHMT 2; Ehmt2; EHMT2_HUMAN; Euchromatic histone lysine methyltransferase 2; Euchromatic histone lysine N methyltransferase 2; Euchromatic histone-lysine N-methyltransferase 2; FLJ35547; G 9a; G9 a; G9a protein; G9A; G9A histone methyltransferase; GAT8; H3 K9 HMTase 3; H3-K9-HMTase 3; Histone H3 K9 methyltransferase 3; Histone H3 K9 methyltransferase3; Histone H3-K9 methyltransferase 3; Histone lysine N methyltransferase; Histone lysine N methyltransferase EHMT2; Histone lysine N methyltransferase, H3 lysine 9 specific 3; Histone lysine N methyltransferase, H3 lysine 9 specific3; Histone-lysine N-methyltransferase EHMT2; HLA B associated transcript 8; HLA-B-associated transcript 8; KMT 1C; KMT1 C; Lysine N methyltransferase 1C; Lysine N-methyltransferase 1C; NG 36; NG36; Protein G9a] |
Gene, Accession # | [EHMT2], Gene ID: 10919, NCBI: NP_001276342.1, UniProt: Q96KQ7 |
Catalog # | MBS9607036 |
Price | $240, $280 |
Order / More Info | EHMT2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |