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Antigenic Specificity | GFRalpha-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: GFRalpha-1 Polyclonal Antibody detects endogenous levels of GFRalpha-1 protein. GFRA1 encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human GFRalpha-1 at AA rangle: 30-110 |
Other Names | [Rabbit GFRalpha-1; GFRA1; GDNFRA; RETL1; TRNR1; GDNF family receptor alpha-1; GDNF receptor alpha-1; GDNFR-alpha-1; GFR-alpha-1; RET ligand 1; TGF-beta-related neurotrophic factor receptor 1] |
Gene, Accession # | [GFRalpha-1], Gene ID: 2674, NCBI: NP_001138925.1, UniProt: P56159 |
Catalog # | MBS9705153 |
Price | $130, $220, $325 |
Order / More Info | GFRalpha-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |