SHP2 (C-TERMINAL) Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | SHP2 (C-TERMINAL) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse, rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | IgG concentration 1.0mg/ml |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This item recognises src homology 2 domain containing tyrosine phosphatase (SHP2), a 68 kDa member of the protein tyrosine phosphatase family. SHP2 acts downstream of growth factor receptors and cytoplasmic protein tyrosine kinases which transduce signals from cell surface to the nucleus. The recruitment and activation of SHP2 is mediated through the binding of CD172a to its ligand CD47.. SHP2 regulates a variety of cellular processes. These include transcription, embryonic development, cell growth, cell migration, differentiation, mitotic cycle, haematopoiesis and oncogenic transformation. As a result, dysregulation of the SHP2 gene has been linked to LEOPARD, Noonan and Noonan-like syndrome as well as acute myeloid leukaemia. SHP2 is ubi |
| Immunogen | Immunogen: 14 amino acid peptide sequence near the carboxy terminus of human SHP2. Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to human SHP2 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Human |
| Other Names | [tyrosine-protein phosphatase non-receptor type 11 isoform 1; Tyrosine-protein phosphatase non-receptor type 11; tyrosine-protein phosphatase non-receptor type 11; PTP-2C; protein-tyrosine phosphatase 1D; protein-tyrosine phosphatase 2C; protein tyrosine phosphatase, non-receptor type 11; Protein-tyrosine phosphatase 1D; PTP-1D; Protein-tyrosine phosphatase 2C; PTP-2C; SH-PTP2; SHP-2; Shp2; SH-PTP3], [PTPN11; PTPN11; CFC; NS1; SHP2; BPTP3; PTP2C; PTP-1D; SH-PTP2; SH-PTP3; PTP2C; SHPTP2; PTP-1D; PTP-2C; SHP-2; Shp2] |
| Gene, Accession # | [SHP2], Gene ID: 5781, NCBI: NP_002825.3, UniProt: Q06124 |
| Catalog # | MBS221486 |
| Price | $375 |
| Order / More Info | SHP2 (C-TERMINAL) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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